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Treatment Options
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Monoclonal Antibodies
Some individuals have a very strong response to substances that cause allergies. Their bodies make too much of a substance known as immunoglobulin E (IgE). When IgE sticks to specific kinds of white blood cells, chemicals that start inflammation are released. In the lungs, these chemicals cause muscles along the bronchioles (tiny airways) to tighten and set off an asthma attack.
The only monoclonal antibody currently available to treat asthma, omalizumab (Xolair), keeps IgE from attaching to other cells and also decreases the places where IgE can stick. Generally not used by itself, Xolair most often is added when inhaled corticosteroids do not control allergic asthma symptoms for adults and teens. It is not for patients under the age of 12 years. It must be injected in a clinic or doctor?s office and up to three injections may be need at a time depending on the patient?s size and the asthma?s severity. Xolair must be injected every 2 weeks or 4 weeks to maintain asthma control. It cannot stop asthma attacks.
Drugs in the class
Omalizumab Solution for Injection
(
Omalizumab (Hamster) Solution for Injection,
Xolair Solution for Injection
)
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Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.
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