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Nitrate and Peripheral Vasodilator Combination

These combination products exert their effects in two major ways. The peripheral vasodilator causes peripheral blood vessels to relax and widen which allows blood to flow more freely. The nitrate is broken down in the body to form nitric oxide, which causes vasodilation. By achieving vasodilation the heart does not have to work as hard in order to efficiently pump blood throughout the body.

Drugs in the class

Hydralazine and Isosorbide Dinitrate ( BiDil Hydralazine Hydrochloride and Isosorbide Dinitrate )


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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