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Proton Pump Inhibitors
Hydrochloric acid is released by the proton pump (ATPase pump) located within the parietal cells of the stomach. Proton pump inhibitors bind to the ATPase enzyme, suppressing gastric acid output. They relieve pain and heal peptic ulcers faster than H2 blockers but are typically more expensive. Unlike the antacids the PPIs don?t offer immediate relief. When a patient uses PPIs the amount of acid released into his stomach is decreased for 3 to 4 days as more proton pumps are inhibited. When the PPI is stopped, the stomach starts producing more acid and is back to normal in 3 to 5 days. Drugs in the class
Esomeprazole Gastro-Resistant Capsules
(
Esomeprazole Magnesium Gastro-Resistant Capsules,
Nexium Delayed-Release Capsules
)
Lansoprazole Delayed-Release Capsules
(
Lansoprazole Delayed-Release Capsule,
Prevacid Delayed-Release Capsule
)
Omeprazole Gastro-Resistant Capsules
(
Omeprazole Delayed-Release Capsules,
Prilosec Delayed-Release Capsules
)
Omeprazole Gastro-Resistant Tablets
(
Omeprazole Delayed-Release Tablets,
Prilosec OTC Delayed-Release Tablets
)
Pantoprazole Gastro-Resistant Tablets
(
Pantoprazole Delayed-Release Tablets,
Pantoprazole Sodium Gastro-Resistant Tablets,
Protonix Delayed-Release Tablets
)
Rabeprazole
(
Aciphex
)
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