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Treatment Options
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ACE-Inhibitor and Calcium Channel Blocker Combination
These combination products combine an ACE-inhibitor and a calcium channel blocker and are helpful for persons who would rather take one pill as opposed to two separate pills.
The kidneys produce the enzyme renin, which releases the hormone angiotensin I. Angiotensin converting enzyme (ACE) converts angiotensin I to angiotensin II, which constricts blood vessels and causes the kidneys to retain more fluid. The main function of angiotensin II is to increase the blood pressure. ACE inhibitors block the conversion of angiotensin I to angiotensin II, thereby reducing constriction and helping to relieve hypertension.
The expansion and contraction of the heart and smooth muscles of the blood vessels are dependent on the movement of calcium into muscle cells. Calcium channel blockers interfere with the uptake of calcium, which then helps to relax and dilate blood vessels, and reduce resistance. Similarly, calcium channel blockers interfere with the uptake of calcium in the heart muscle, slowing the contraction of the heart and making the contractions less intense. Because of how they work, calcium channel blockers are commonly used to treat hypertension and sometimes used to treat coronary heart disease. Drugs in the class
Amlodipine and Benazepril
(
Lotrel
)
Verapamil and Trandolapril
(
Tarka
)
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Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.
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