|
Sexually Transmitted Infections (STIs)
What is on the horizon?
Chlamydia
Scientists are looking for better ways to diagnose, treat, and prevent chlamydial infections. Scientists have recently discovered new information (genes, DNA, structure) about the organism. This new information about the organism will help scientists create a safe and effective vaccine. Developing topical microbicides (preparations that can be inserted into the vagina to prevent infection) that are effective and easy for women to use is also a major research focus.
Gonorrhea
Scientists are continually trying to understand how the bacterium attaches to the human cells, how it gets inside the cell, and the structure of the bacterium in the hope of developing a vaccine. With an increase in drug resistance to the bacterium, research is continually being done to develop newer and more effective antibiotics.
Syphilis
Scientists are continually developing better ways to diagnosis and treat syphilis. With the new advances that are being studied in diagnosing syphilis, scientists are hoping to be able to define the stage of syphilis. Also, work is being done to study the structure of the bacterium to develop a safe and effective vaccine. As for all infectious diseases, researching newer, safer antibiotics is also being done.
Trichomoniasis
The number of cases of metronidazole-resistant trichomoniasis appears to be increasing rapidly. Some success has been reported with the broad-spectrum anti-parasitic drug nitazoxanide, but further research needs to be done. A group of researchers in Thailand is currently investigating the effectiveness of a group of drugs known as bisquaternary quinolinium salt compounds in treating trichomoniasis.
Genital Herpes
There is research being conducted in which clinical trials have demonstrated that once-daily suppressive therapy using valacyclovir significantly reduces risk of transmission of genital herpes to an uninfected partner. This is the first time an antiviral medication has been shown to reduce the risk of transmission of an STI. This strategy may contribute to preventing the spread of genital herpes.
|