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Helping Yourself
Sleep Disorders

How is it treated?

Drug therapy in combination with good sleep hygiene (click on the Helping Yourself box) may be helpful for short-term management of insomnia.

Over-the-counter sleep aids that contain diphenhydramine (Benadryl), an antihistamine, may be helpful for short-term bouts of insomnia. Because the body can grow accustomed to antihistamine sleep aids, they often lose their effectiveness the more you take them. If you experience continued bouts of insomnia you should talk to your doctor to see if prescription medications are needed. Benzodiazepines are commonly used for the management of sleep disorders. Short-acting benzodiazepines are less likely than long-acting benzodiazepines to be associated with drowsiness or sluggishness the next morning. Benzodiazepines are only available with a prescription. They are controlled substances and do carry a potential for addiction if used inappropriately.

Other drugs used in the management of insomnia include unique agents called non-benzodiazepine sedative hypnotics. Examples include Ambien (zolpidem), Sonata (zaleplon), and Lunesta (eszopiclone).

Drug classes also considered sedative hypnotics are barbiturates and sedating antihistamines. The non-benzodiazepines and barbiturates are also controlled substances due to the potential for addiction.

A new class of sedative hypnotics has recently been introduced to the market. Rozerem (ramelteon),is a melatonin receptor agonist which mimics the body?s natural sleep promoting hormone, melatonin. This drug class is unique because it works with the body?s natural circadian rhythm to promote sleep. These melatonin receptor agonists do not carry an addiction potential.

Natural remedies have been used for years to treat sleep disorders. One of the most popular "natural" remedies for insomnia has been melatonin, which can be obtained at most pharmacies and health food stores. Melatonin is a hormone that is known to be involved in the regulation of sleep and wakefulness. It has been shown that the ingestion of melatonin prior to bedtime will help individuals fall asleep. However, scientific data have failed to confirm that melatonin is useful in maintaining sleep.

Herbal products such as valerian, chamomile, kava kava, and others have also been promoted as natural remedies for insomnia. However, the effectiveness and safety of these products has not been documented in large clinical trials.

Drug classes used to treat Sleep Disorders

Barbiturates

Benzodiazepines

Miscellaneous Sedatives and Hypnotics

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Last Updated: October 2007
This content was created by members of the DrugDigest team of experts and is solely under DrugDigest's editorial control.


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.

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